When to Use Blended Tinctures

By Billee Sharp

Tinctures are the mainstay of many traditional medicine modalities, medicinal herbs can be preserved intact in an alcohol solution or an oil.

Tincture makers refer to the herb as the ‘marc’ and the carrier oil or alcohol as the ‘menstruum’. Accordingly the most important ratio in this process is the ratio of the “marc’ to ``menstruum” as this will determine the strength and concentration of the tincture.

In nineteenth century America cannabis tincture was commercially produced and a popular cure for all sorts of conditions; from menstruation pain to inflamed joints, toothache and neuropathy. Dr J. Russel Reynolds, physician to Queen Victoria, believed it to be curative for many conditions, particularly migraine, he wrote,

“Very many victims of this malady (migraine) have for years kept this suffering in abeyance by taking hemp at the moment of threatening, or onset of the attack”.

Throughout the 1800s many articles were written by physicians in medical journals recommending cannabis tincture but popularity for cannabis preparations declined after 1890. The inability to control the variability of cannabis strength and composition and the unpredictability of a patient's response were issues and cannabis medicine was superseded by the introduction of aspirin, chloral hydrate and barbiturates.

Now modern medical science has revealed the ECS and the constituent values of cannabinoids so that now tinctures can be made with precise knowledge of the cannabinoid constitution of any given plant source.

Tincture is a quick onset treatment, drops taken sublingually are absorbed into the bloodstream where rapid uptake means symptom relief is felt within twenty minutes, often faster.

The science of cannabinoids is still in its infancy, there are over a hundred recognized cannabinoids but only ten or so are under scientific study as yet. THC (Delta-9 Tetrahydrocannabinol) is the most well known cannabinoid, as its psychoactive effects have made it the relaxant of choice for many. THC also has significant medical value and is particularly valuable in cancer treatment and alleviating chronic pain. The psycho-activity can be reduced by the addition of CBD which moderates the ‘high’ by competing for receptor space with the THC.

CBD, with its ability to reduce inflammation and anxiety without psycho-activity has become a major contributor to cannabis medicine, not only tinctures but also topicals and edibles have become extremely popular as viable alternatives to opiates and synthetic pharmaceutical drugs.

The more we’ve learned scientifically about cannabinoids the more refined treatments have become. Consider the recent discoveries of CBG, CBDV, , CBN, THCV and the acid forms : CBGA, CBDA, THCA, which studies show have increased bioavailability and actions on specific conditions. THCV for example which has shown great promise in Parkinson's symptoms, tremors and neuro-regeneration.

This preamble leads to Synergy’s range of blended tinctures and why we recommend blended cannabinoids for various conditions. Blended tinctures are defined by their constituent cannabinoids and the ratio that they are combined at. For example, a 1:1 ratio of CBD to THC combines the actions of both CBD and THC and they also act on each other; the CBD moderates the psycho-activity of the THC but doesn’t interfere with its other functions.

Synergy’s blended tinctures have been developed through Leonard Leinow and Dr Muscowitzs' understanding of the needs of our community. Many members suffer from debilitating pain but are cautious about psychoactive effects. In this case our 4:1 CBD:THC blend would likely be suggested, this ratio rarely induces a psychoactive effect and has a powerful analgesic effect on acute and chronic body pain while also reducing inflammation and anxiety. Synergy offers the 4:1 blend two ways; #103,104, 105 4:1 blend is made with Indica dominant THC, which yields deep pain relief and sleep benefits. #116 4:1 uses Sativa dominant THC with energetic properties which support daytime pain relief combined with uplifting mental benefits from CBD, this blend has also been noted for its anti-nausea action.

A blended tincture can reflect more than two cannabinoids in its constitution. Synergy’s #135 Cleopatra Blend tincture illustrates this, the ratio of 5:3:1 CBD:THC:THCV was created to particularly address tremors, this blend’s anti-spasmodic effects combine with pain relief and anti-inflammatory action, There is a mild psycho-activity associated with this blend and members have reported excellent sleep with night time use.

In a similar way #160 CBD Medley tincture combines CBD from four CBD rich strains, this increases the variety of terpenes available giving a full expression to the benefits of CBD.

The longstanding popularity of the classic #154,#155,#156,#165 Balance 1:1 CBD:THC blended tincture attests to the effectiveness of this combination, indicated for relieving pain, inflammation, muscle spasm, tremor, mental agility, digestive issues, anxiety, insomnia and nerve pain.

A higher ratio of THC increases the psycho-activity of tinctures but not everybody finds that problematic. The complementary effects of pairing THC with CBD have produced successful results in extremely compromised conditions. Synergy’s #210 THC: CBN 1:1 tincture is a good example of a balanced blend with mild psycho-activity reported, with sedative, appetite stimulation and immune regulation properties.

Through research the science of cannabinoids is becoming more precise and our knowledge of the benefits of combining cannabinoids is growing exponentially. Currently Synergy Wellness curates one of the largest selections of medicinal cannabis tincture blends available and more blends are in development. As always we recommend close attention to titration and keeping notes on effectiveness of dosages to yield the best results.

Lentil Waldorf Salad with a CBD-infused Dressing

The intense heat of the summer months can wreak havoc with our appetite, with hot food often feeling heavy and unappealing. This is when salads come into their own, light and easy to prepare, salads can easily become the focus of summer meals. From a simple green salad with seasonal goodies like tomatoes and cucumbers to wholesome protein rich salads like a lentil waldorf with green lentils, celery and apple.

This lentil salad is light and protein-rich easy to make and addictive with the zesty dressing. This dish will refrigerate well but it never lasts long its perfect for snacking with cheese and crackers too. The CBD-infused dressing will work with any fresh salad if lentils aren’t your thing!

Ingredients

1 cup small green lentils, french are best as they keep their form when cooked.

3 diced apples, of your choice

3 stalks of celery

½ cup chopped parsley

I cup of CBD-infused Dressing ( ingredients and instructions below)

1. Wash and sort the lentils then bring to a boil in water with a pinch of salt (optional) then only take ten minutes or so, keep an eye on them because overcooking will turn them to mush. Drain and set aside.

2. Dice the apples into dainty cubes, I keep the peel on for extra fiber and the added color. Chop the celery into slim slices, if the stalk is wide, cut it in half lengthways and then chop.

3. Chop the parsley and then mix all the ingredients together and set aside.

CBD-infused Salad Dressing

Ingredients:

4 tablespoons olive oil

2 tablespoons hemp seed oil

20-30 drops Synergy CBD-rich tincture

Juice of one lemon

½ teaspoon dijon mustard

½ teaspoon nutritional yeast

4 tablespoons vegan mayonnaise ( or your favorite)

I clove finely chopping garlic (optional)

Salt and black pepper to taste

Mix all the oils and lemon juice together in a medium sized bowl, add in the other ingredients one by one and leave the mayonnaise until last. The consistency should be thick but pourable - add a little more oil or lemon juice if needed.

Combine the lentil salad with the dressing, it will look very appetizing. Best to chill for half an hour for the best flavor, garnish with parsley.

Can Cannabis Help Treat Depression?

There’s much more to it than taking a hit when you’re blue

By Dan Reich

Depression is a pervasive health issue, affecting an estimated 260 million people worldwide. Patients suffering from depressive disorders experience a wide range of issues, including sadness, anxiety, guilt, irritability, impaired memory, thoughts of death and suicide, loss of motivation, disturbed sleep or appetite, as well as tiredness, neglect of responsibilities, changes in personal appearance, and withdrawal from others. Current antidepressant medications often fail to offer long-term relief, as perhaps a third of all patients develop resistance to the medications, which can take weeks to offer relief from symptoms and come with unpleasant side effects, including weight gain, loss of libido and more. Given this spotty history, many people with depression have difficulty finding relief via conventional treatments. Often an unpleasant experience using high-THC cannabis will mean there is resistance to trying a cannabis treatment for depression but CBD is not psychoactive and doesn’t induce anxiety.

A fair amount of research has gone into determining whether CBD has promise in improving the lives of those suffering from depression. Depression is believed to be caused – at least partly – by a lack of serotonin in the brain. CBD doesn’t necessarily boost serotonin levels, but it may affect how your brain’s chemical receptors respond to the serotonin that’s already in the body’s system, as it binds to serotonin receptors.

Researchers have discovered that CBD can be effective in addressing many conditions that contribute to depression, such as stress, insomnia, anxiety and PTSD. A 2018 NIH study concluded that CBD has anti-stress effects, which may reduce depression related to stress. Both CBD and THC have shown effectiveness as a sleep aid, and research has shown that CBD can reduce levels of anxiety significantly. In a clinical trial carried out in adults diagnosed with PTSD, CBD plus psychiatric medications and psychotherapy reduced the severity of PTSD symptoms after 8 consecutive weeks of treatment.

At the very least, the calming and sense of well-being that CBD can induce has produced a lot of anecdotal evidence that people with depression can obtain relief from CBD, or even from balanced cannabis strains that combine CBD and THC in a 1:1 ratio. (The CBD counteracts the anxiety-inducing properties of THC for many people.)

“Anxiety and depressive disorders are highly prevalent," says Erin L. Martin, a PhD candidate at the Medical University of South Carolina. "Traditional antidepressants may effectively treat these disorders in a lot of people, but they do not work for everyone and can have unpleasant side effects. Medicinal cannabis products, especially products high in CBD, may help to treat symptoms of depression, improve sleep, and increase quality of life. There is also some evidence that medicinal cannabis may alleviate symptoms of anxiety, particularly if administered over an extended period of time, but this is less clear from our results and warrants further study.

Getting the right balance of THC to CBD is important. "When it comes to sleep, generally that means identifying a strain that contains relaxing terpenes, and a balance of CBD and a not-too-high concentration of THC," says Michael Breus, PhD, the resident sleep expert on WebMD.

Terpenes that show particular relaxation properties include Limonene, a citrus-flavored terpene found in citrus peels as well as in cannabis and other plants, which has been shown to reduce anxiety and stress. Limonene may also have anti-depressant effects. Scientists think its calming, mood-lifting effects come from limonene’s ability to elevate serotonin levels in the brain.

Linalool, a lavender-scented terpene found in hundreds of plants, including cannabis, is an established relaxation and sleep aid. Studies show linalool can lower anxiety and depression symptoms, as well as help guard the immune system against damage from stress.

Synergy Wellness has a reputation as a specialist resource for CBD-rich supplements, curating many CBD-rich cannabis strains, including the Synergy -Tsu strain which was developed in-house and tests at 22:1 CBD/THC. A daily protocol of a high CBD preparation can yield significant results in mood enhancement without unpleasant side effects. A dose of CBD-rich tincture taken sublingually and then swallowed will elicit a rapid onset within twenty minutes, quickly relieving anxiety and tension. Similarly CBD-rich raw capsules are useful for delivering long-lasting relief from symptoms. CBD-rich cookies are a tasty popular choice with a sustained effect, while others prefer the rapid onset of a CBD-rich vape pen. Different CBD-rich strains have various terpene and cannabinoid profiles which is why Synergy Wellness is proud to offer such variety in their products.

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